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Republic of Ireland captain Seamus Coleman is due to undergo surgery on Saturday as he faces a lengthy spell on the sidelines.
Press Association Sport understands the 28-year-old Everton full-back suffered a double fracture of his lower right leg during Friday night's 0-0 World Cup qualifier draw with Wales at the Aviva Stadium in Dublin.
Coleman was hurt in a challenge by Wales wing-back Neil Taylor, who was sent off as a result, 69 minutes into a stormy affair.
He was treated at length on the pitch and was given oxygen as he was comforted by team-mate Shane Long, and eventually left on a stretcher.
Coleman was taken straight to St Vincent's University Hospital in the city, where he was due to have screws inserted to help repair the damage on Saturday.
Chris Coleman defended Neil Taylor after Republic of Ireland defender Seamus Coleman was left with a broken leg in their fierce World Cup qualifier in Dublin.
The Everton full-back was carried from the field on a stretcher after Taylor had been shown a straight red card for his 69th-minute tackle during Friday night's goalless draw.
The Football Association of Ireland confirmed later that Coleman had broken his right leg and the Republic captain is expected to undergo surgery on Saturday.
Television underlined the severity of the injury by choosing not to show replays of the incident which ended Coleman's season.
"Sadly for Seamus, obviously, it looks like it's a bad one," Wales manager Coleman said, adding Taylor had gone into the Republic dressing room at the end of the match to see the Ireland captain.
"Neil Taylor is not that type of player. He's had a serious injury himself. He's a great boy, he's a cracking lad. I've not seen the challenge, but I've seen the outcome, if you like, and it's a bad one for Seamus.
"Yes, it looks like he (Taylor) has got that one wrong on our part. I've only seen it in real time when it happened and I didn't see a lot. I saw the reaction. I have seen a picture of the outcome, so my thoughts are with Seamus.
"Of course, Neil is devastated himself. But, no, I never said to Neil, 'What were you thinking?'"
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Wales boss Chris Coleman has told Republic of Ireland to forget about trying to goad Gareth Bale in their World Cup qualifier.
Real Madrid forward Bale returns from a two-match La Liga ban at Athletic Bilbao on Saturday after being sent off against Las Palmas.
Bale picked up the second red card of his career for shoving Las Palmas midfielder Jonathan Viera to the ground during an ill-tempered 3-3 draw.
But Coleman is confident Bale will keep his head in the white-hot atmosphere of Dublin's Aviva Stadium next week.
Anybody sensible looking at him will see he never does that. I don't even know what happened. But he is a human being and sometimes you do something and regret it.
If you look at his past, though, and he has been kicked from pillar to post, I won't be worried.
I remember when we played Scotland and some ex-Scottish player said, 'He can't play if he hasn't got any legs.'
I looked at that and thought, 'Does he really seriously think that is going to bother him?' If you look and see where he is playing, under the pressure, in the spotlight, week in, week out...
So whatever the opposition have got planned for him, he's seen it before and dealt with it before. I'm not at all worried.