It was another battle to the end, but it was Roger Federer who took the tie-break victory in the second set.
The Swiss player won 12-10 on the tie-break after an epic set on centre court.
Novak Djokovic needed a tie-break in order to win the first set 7-6 against Roger Federer.
Celebrities better known for appearances in Hollywood stars arrived at SW19 to watch Roger Federer and Novak Djokovic battle it out in the Wimbledon final.
Benedict Cumberbatch, Bradley Cooper and Hugh Grant were in the Royal Box on Centre Court alongside a host of former Wimbledon champions. Sherlock star Cumberbatch, 38, was joined by his father Timothy, while 54-year-old Grant was sat with TV executive Anna Eberstein, the mother of one of his three children. Oscar nominee Cooper, 40, was in the exclusive box after previously sitting with Federer's camp during the tournament.
Jamie Murray and his Australian partner John Peers have lost the Wimbledon men's doubles final in straight sets.
They were beaten 7-6, 6-4, 6-4 by fourth seeds Jean-Julien Rojer from the Netherlands and Horia Tecau from Romania.
Murray and Peers have earned £170,000 as runners-up.
His brother Andy and sister-in-law Kim stood and applauded from the stands as the pair left the court.
Serena Williams now holds all four majors for the second time in her career, after dispatching Garbine Muguruza.Read the full story ›
Garbine Muguruza was no match for Serena Williams in the end, as the American earned her sixth Wimbledon championship.
The young Spaniard started well, but Williams began to dominate, taking the first set 6-4.
Williams looked set to ease to the win when she was 5-1 up in the second, but Muguruza fought back to 5-4, but Williams broke back to win 6-4.
After a promising start from Garbine Muguruza, Serena Williams fought back to eventually take the first set 6-4.
Gabrine Muguruza will face five-time champion Serena Williams in the ladies Wimbledon singles final today.
Williams, 33, is eyeing her sixth singles title and to complete a second "Serena slam" - holding all four major titles at once.
Meanwhile, the 21-year-old Spaniard will be playing in her first ever Grand Slam final.
Muguruza beat Williams 6-2 6-2 in the second round at the 2014 French Open.
Andy Murray is out of Wimbledon after being beaten by Roger Federer in straight sets in their semi-final.
The Swiss second seed set up a final showdown with world number one Novak Djokovic by beating Murray 7-5, 7-5, 6-4 on Centre Court.
Roger Federer moved to within one set of the Wimbledon final after going 2-0 up against Andy Murray.
Murray saved five set points during a marathon game to hold his serve and make it 5-5 in their semi-final.
However, Swiss Federer then held his serve with ease before breaking Murray and taking the set 7-5.