Park chiefs said the double-walled design of the affected cabins made it easy for mice to nest between the walls. The disease is carried in the faeces, urine and saliva of deer mice and other rodents and carried on airborne aerosol particles and dust.
The 91 insulated canvas cabins in the century-old Curry Village are new to the park, built in 2009 to replace some that had been closed or damaged after parts of Curry Village, which sits below the 3,000ft Glacier Point promontory, were determined to be in a rock-fall hazard zone.
Park staff found evidence of mouse nests in the insulation while taking them apart for cleaning.
Up to 10,000 people who stayed in lodging cabins at Yosemite National Park in California may have been exposed to a deadly mouse-borne virus that has killed two people.
Park concessionaire Delaware North sent letters and emails this week to nearly 3,000 people who reserved the insulated Signature cabins between June and August, warning them that they might have been exposed.
The cabins hold up to four people and park spokesman Scott Gediman said that could mean up to 7,000 more visitors may have been exposed to the virus that so far has killed two people and made four others ill.
Meanwhile, more than 1,000 calls a day are coming into the national park as visitors frightened about the growing outbreak hantavirus pulmonary syndrome call seeking answers.