Flood alerts have been issued for large areas of the region.
The Met Office is warning that a month's rain could fall within 24 hours.
Heavy downpours are forecast the worst of them later tonight.
Places such as Barnard Castle have already been affected by the down pours.
Businesses have been damaged with rain water and streets flooded.
Hardware Store owner, Dave Wilson must close his shop in Barnard Castle for a few days to start clearing up the damage that has been caused.
Perry Clifton who owns the The Orchard Greengrocer's in Barnard Castle has never seen anything like it.