A boy from Sunderland is to become one of the first people ever to take part in a new study of Mucopolysaccharidosis (MPS) III.
Four-year-old Jack Baird has the condition, which is also known as Sanfilippo Disease.
It is a progressive, genetic and life-threatening disease which affects around one in 85,000 people in the UK.
There is currently no effective treatment for the illness which is diagnosed in childhood.
Those with the condition experiencing deafness, hyperactivity and behavioural problems, progressive developmental delay, and seizures during the later stages of the condition.
The condition is usually fatal in late childhood or early adulthood.
Researchers at The Royal Manchester Children’s Hospital and The University of Manchester have recruited Jack as the first child in their new study.
The study aims to evaluate the clinical effectiveness of a treatment developed in Manchester, which could alter the lives of patients with Sanfilippo Disease.