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The NHS body in York which has controversially voted not to pay for IVF treatment for childless couples, says offering help to the estimated 110 couples a year would have cost it around £2m.
Campaigners have criticised the decision by the Vale of York Clinical Commissioning Group, which says it is facing a funding shortage and has to make "tough choices."
It means York is the only area in the UK where women struggling to conceive are denied fertility treatment on the NHS. Critics say that childless couples in the area are victims of a health service postcode lottery - and they are calling for York to fall in line with national guidelines which state that 3 cycles of IVF should be offered to people who match the criteria up to the age of 39.
The NHS in York says it has taken the decision with "a heavy heart", but "the commissioning of IVF services carries a great element of financial risk."
An IVF campaigner from York says she is devastated by the decision by NHS bosses in the city not to fund the treatment.
Karen Boardman, 34, from Heworth, has fought against what she calls the "postcode lottery" regarding the treatment, and helps run the York Fertility Network group.
In June, the NHS Vale of York Clinical Commissioning Group's governing body agreed a policy of offering one cycle of IVF to people who met their criteria. But last night NHS managers said there was not enough money to fund the service.
Mrs Boardman said: "I don't know how they can snatch it away from us."
The NHS in York has backtracked on a decision earlier this summer to offer childless couples IVF treatment. The city is the only place in the UK not to offer at least one cycle of IVF.
In June, the NHS Vale of York Clinical Commissioning Group's governing body agreed a policy of offering one cycle of IVF to people who met their criteria. It followed years where the treatment had been denied to people in the area because NHS managers said there was not enough money to fund the service.
But today the governing body narrowly voted not to introduce IVF treatment this year. They will look again at the issue at the end of this financial year.