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Thousands of junior doctors have gone on strike yet again, this time for 48 hours.
It's the longest strike so far lasting until Friday morning.
The ongoing row with the government is about changes to junior doctors' contracts.
While A and E isn't affected, many operations and outpatients appointments across the North East have had to be cancelled.
We spent the day with Peter Campbell, a junior doctor, who says they have no option but to strike.
Watch the report from our correspondent Frances Read:
The Department of Health says no doctor working contracted hours will receive a pay cut under the new contracts.
Meanwhile NHS England says it is doing everything possible to ensure safe emergency care is being provided and to minimise the impact of the latest industrial action.
A new survey ahead of today's walkout by suggested nine in 10 junior doctors could quit if the current contract terms were imposed.
According to The Independent, an online poll found that:
New contracts could be imposed on junior doctors by the Health Secretary after union leaders rejected his "best and final offer".
The Government's chief negotiator, Sir David Dalton, had warned talks were at "the end of the road" should the British Medical Association not endorse his latest offer by Wednesday afternoon.
Instead the BMA again called on the Health Secretary to accept its own proposed pay model and withdraw his threat to force through changes, even though the Government has refused to "remove that from the table".
A 24-hour strike by medics will end at 8am today.
The shadow health secretary has urged Jeremy Hunt to negotiate with junior doctors and find a resolution to the dispute.
Heidi Alexander said the industrial action is "deeply disappointing" and the "sad truth is that it didn't have to come to this".
Junior doctors have walked out for a second 24-hour strike amid a bitter row with the government over pay and conditions.
But how do you feel about the junior doctors' strike? Take our poll and have your say.
Junior doctors have been told what to do if a trust declares a major emergency during the strike.
During the last junior doctors' strike, Sandwell Hospital in West Bromwich declared a level 4 incident and told its junior doctors they must attend work.
According to the letter, junior doctors can be requested to work if:
- There is both "exception and sustained deterioration in performance such as to endanger patient safety and cannot be managed through the deployment of the hospital’s senior hospital doctors and the junior doctors providing emergency care".
- The Trust must make a formal request to NHS England, who will then contact the BMA.
The NHS is "doing everything possible to minimise the impact" of the junior doctors' strike, the national incident director for the NHS said.
She said the NHS "anticipates around 2,800 operations will be cancelled".
She added: "To put that into context - on an average day the NHS does 31,000 operations so the vast majority will go ahead."
Junior Doctors across the region are striking after talks with the Government failed to reach an agreement. These pictures were taken by one of our reports outside the Royal Victoria Infirmary in Newcastle.
The action is part of an ongoing row with the Government over contract conditions.
Latest ITV News reports
The health secretary says he hopes he does not have to enforce junior doctors' contracts, as second wave of strikes takes place.
Junior Doctors across the region are set to go on strike this morning after talks with the Government failed to reach an agreement.