Mo Farah has claimed first place in the elite men's event, crossing the line at South Shields with a personal best time of 60 minutes and 1 second.
Kenyan distance runner Mary Keitany has won the women's elite event at the Great North Run, with a finishing time of 65 minutes, 39 seconds.
Britain's Gemma Steel claimed second place.
British Paralympic athlete Shelly Woods was first across the finish line in the women's wheelchair event, with a time of 50'34".
Mo Farah has set his sights on winning this year's elite event at the Great North Run.
He joins top athletes from all over the world, setting off before the main event in which the millionth runner to take part in the Great North Run will cross the finish line.
The Great North 5km started a weekend of athletes across Tyneside.
Top athletes James Cracknell and Stephen Kiprotich started the race around the Newcastle Gateshead Quayside at just after 9am this morning.
Winners Elizabeth Hodgkinson and Marc Fenwick received their trophies at the end of the race.
The 5km race was followed by theGreat North Mini Run with more than 6,000 children taking part.
Elite athletes from all over the world later competed around the Quayside in the City Games.
Around 6,500 children have competed in the Great North Mini Run, the UK's biggest children's running event.
Youngsters aged 3-16 completed the course around the Newcastle Gateshead Quayside.
Postman Pat fired the starting gun, and athletes running in tomorrow's Great North Run were at the start line inspiring the next generation.
To enable the safe running of the race the following road closures will be put in place over the weekend.
Below are the details of all road closures:
SATURDAY 6TH SEPTEMBER
- 17:00 until 07/09/12 17:00 - A167 From Cowgate Roundabout to Great North Road Junction(B1318)
SUNDAY 7TH SEPTEMBER
- 08:45-17:00 - A167(M) Central Motorway including Tyne Bridge + B1318 Great North Road to A184 Park Lane
- 09:00-17:00 - A184 Felling By-Pass to Whitemare Pool Roundabout and A194 Leam Lane
- 09:45-16:00 - A194 Leam Lane from Whitemare Pool to A1300 John Reid Road Roundabout
- 09:45-16:00 - A1300 Prince Edward Road Roundabout to A183 Redwell Lane/Coast Road A183 Roundabout
- 09:00-17:00 - A183 Redwell Lane/Coast Road Roundabout to Roundabout with Sea Road and Mowbray Road
- 02:45-17:00 - Bents Park Road in South ShieldsDiversion routes will be fully signposted, but some disruption is inevitable.
Drivers are advised to take alternative routes wherever possible.
The Tyne Bridge and the Gateshead Highway are expected to re-open by 14:00hrs providing links to routes via the A184 Askew Road and Consett Route to the A1 and South via the A167 to Low Fell and Eighton Lodge.
A North-South route from Sunderland Road (B1426) to Shields Road (A195) across Heworth Roundabout will be opened as soon as the last runners have cleared the Junction.
Before 17:00hrs, the remainder of the A184 route between Gateshead and the White Mare Pool (A194/A194(M)) Interchange will re-open, once the route has been cleaned and all event infrastructure has been removed.