Former PM Tony Blair has paid tribute to Lady Thatcher:
“Margaret Thatcher was a towering political figure.
Very few leaders get to change not only the political landscape of their country but of the world. Margaret was such a leader. Her global impact was vast.
And some of the changes she made in Britain were, in certain respects at least, retained by the 1997 Labour Government, and came to be implemented by governments around the world.
As a person she was kind and generous spirited and was always immensely supportive to me as Prime Minister although we came from opposite sides of politics.
Even if you disagreed with her as I did on certain issues and occasionally strongly, you could not disrespect her character or her contribution to Britain’s national life.
She will be sadly missed.
Labour leader Ed Miliband has said British politics will be a "poorer place" following his brother David's decision to step down as an MP.
The former foreign secretary, and the elder of the Miliband brothers, announced this morning that he will be moving to New York to become head of a US-based charity.
ITV News political correspondent Alex Forrest reports:
Sunderland football club has said David Miliband will continue as vice chairman and non-executive director, despite quitting as a Labour MP for South Shields:
David Miliband told ITV News "I am leaving politics" as he steps down as an MP to take on a charity role based in New York.
He admitted life had been tough since losing the leadership election to his brother Ed.
Political Editor Tom Bradby began by asking him whether the move means an end to his political career:
The former Foreign Secretary David Miliband has told ITV News: "I am leaving politics."
He told political editor Tom Bradby it is "not fair for me to spend my time looking backwards and inwards" about losing the Labour leadership election to his brother Ed.
He denied any falling out with his brother: "We fought a leadership election but we don't fight each other, Ed and I. That's not the Miliband way."
But he admitted: "Is it tough? Of course it's tough."
He said he "kept him [Ed] informed" about his new role.
David Miliband's local Labour party has said they want to choose their own MP, something he said they have not done in living memory.
John Anglin, secretary for the Constituency Labour Party in South Shields, said: "We are very surprised and it's a great loss to the Labour Party but that is what he has decided to do.
"He's done a lot of good work up here, with schools especially, but he's got a family and he knows what he wants to do.
"We wish him all the best but now we have to concentrate on South Shields and make sure we get a good MP.
"We want to make sure we are allowed to choose our own MP, something we have not done in living memory.
"We have a Labour-run council, which is doing great work, and we have the people up here who are capable of becoming an MP."
Bill Clinton has congratulated David Miliband on his appointment with the International Rescue Committee.
He said: "I congratulate the IRC on the appointment of David Miliband as its president. I have known David almost twenty years. He is one of the ablest, most creative public servants of our time."
Ed Miliband has said the "door was open" for his brother David to return to front line politics but he has taken the decision to take on a new role based in New York. The Labour leader said his brother will be "serving the world" with his new charity position:
Former Prime Minister Tony Blair has paid tribute to David Miliband, following news of his resignation as an MP.
"I congratulate David on his appointment to a major international position. It shows the huge regard in which David is held worldwide. I'm sure he will do a great job. He is obviously a massive loss to UK politics.
"He was the head of my policy unit and then a truly distinguished Minister in the Government and remains one of the most capable progressive thinkers and leaders globally. I hope and believe this is time out not time over."