"Robust plans" are in place to protect patients during a four-hour strike by thousands of health workers today, NHS England said.
Around 150 police officers will drive or help crew ambulances in London as part of the plans, with paramedics among those walking out in the row over pay.
NHS organisations have tried and tested plans to deal with a range of disruptions including industrial action.
We are working with the NHS to ensure there are robust plans for November 24 that protect the safety, welfare and service provided to patients.
NHS workers will stage a four-hour strike today in a row with the Government over pay.
Midwives, nurses, radiographers, paramedics and psychiatric staff will walk out from 7am in England and 8am in Northern Ireland in protest at the Government's refusal to accept a recommended 1% wage rise for all NHS employees.
Unison leader Dave Prentis said the second strike in a month should "sound alarm bells" in Westminster as the "anger is spreading".
A Department of Health spokesperson said the government "can't afford a consolidated pay rise in addition to increments without risking 10,000 frontline jobs".
Today is the second day of action for NHS staff in our region - including midwives, who walked out on strike for the first time ever yesterday in a row over pay.
Today, union members from Yorkshire and Lincolnshire will follow yesterday's four-hour walk-out with four days of "work to rule".
Tony Pearson, from Unison Yorkshire and Humberside, explains that it is to demonstrate NHS workers often work through their breaks.
Trade unions want a 1% pay rise for all NHS staff, but the government says that will cost too much.
Cat Rowney, an NHS midwife at Newcastle's RVI hospital, has spoken of the anger she and fellow hospital workers across the North East feel.
It has got very bad in the last few years, we're in a decade long baby boom at the moment so there's more and more babies being born with less and less staff.
People aren't encouraged to come into midwifery anymore because of all the issues that are going on. We work very long hours, we often work unpaid overtime, we don't get breaks, we don't get to have anything to eat, we don't get to go to the toilet.
It's got to the point where enough's enough and we need to make a stand and let everyone hear our voice.
NHS workers at Leeds General Infirmary who have taken part in today's four hour strike have said industrial action is a last resort.
Edward Barr from Unite, Matthew Barker who is a porter, Fiona Powell, an NHS worker and midwives Liz Furness and Anita Marshall, have been speaking to ITV Yorkshire about why they chose to strike.
Turnout at the entrance to the Royal Victoria Infirmary is about 80 people.
"I'm really impressed with the turnout. The atmosphere is absolutely fantastic and everyone is pulling together to make it clear to the Government that we deserve this pay rise."
Midwives at the Royal Victoria Infirmary in Newcastle go on strike for the first time in their union's history.
They say the Government has treated them with contempt.
Jeremy Hunt has defended the Government's handling of the NHS pay dispute this morning.
He said: "We have to make sure we end up with a decision that isn't going to lead to nurses and frontline staff being laid off."
Around 40 NHS workers are outside Newcastle's Royal Victoria Infirmary in protest over pay. They are chanting "what do we want? More pay" - The walk out will last for four hours.
Health secretary Jeremy Hunt has said the government is prepared to talk to the striking NHS unions about the current pay rise dispute.
He said: "We will talk to them if they're prepared to look to reform the system of increments, which is unclear and unfair.
"I recognise frontline staff do a magnificent job in the NHS."