Scotland has said no to independence, rejecting the Yes campaign's vision to break away from the UK.
45% of people voted yes but 55% said no. Scotland's First Minister Alex Salmond has announced he is resigning. He will step down in November.
But what does the result mean for us, in the North East of England?
David Cameron has already promised more say for the English regions and today there has been a clamour of calls for the North East to have far greater control of its own affairs. We will be looking at that in more detail in a moment.
ITV Political Correspondent Paul Brand looks at the reaction in Westminster, and what happens next:
As we take in the political implications of the referendum result, the North East business community is assessing the economic impact on our region.
Overall, firms say the No vote provides much needed stability, but there are still questions to be answered about the road ahead.
Helen Ford examines the reaction of the North East economy:
Aside from the economic and political arguments, nowhere in the North East region has been more aware of the implications of the referendum result than the town of Berwick in the far north of Northumberland.
Kenny Toal has spent the day there, following Scotland's decision to reject independence:
Further devolution in Scotland without similar powers for the North East could be bad for business, according to one of the region's leading business figures.
Fergus Trim, Development Director at Quorum Development Partners, said: "If we can mirror what's being offered in Scotland and take more control of the economy here, then that will be positive for us."
Nicola Sturgeon has said that in the aftermath of Alex Salmond's resignation as First Minister, it would be a "privilege..to seek to lead the Party."
"Alex's announcement today inevitably raises the question of whether I will be a candidate to succeed him as SNP leader.
"I can think of no greater privilege than to seek to lead the Party I joined when I was just 16. However, that decision is not for today.
"My priority this weekend, after a long and hard campaign, is to get some rest and spend time with my family.
"I also want the focus over the next few days to be on the outstanding record and achievements of the finest First Minister Scotland has had.
Alex Salmond was pictured looking disappointed in the early hours of this morning after results started to point towards a victory for the No campaign.
Scotland's First Minister was shown being driven through a side entrance to a private plane at Aberdeen Airport.
Early results and final polling had indicated that Scottish voters were most likely to have rejected independence in yesterday's vote - perhaps explaining the apparent dejection on Salmond's face.
Alex Salmond today said he would be standing down as Scotland's First Minister and Scottish National Party leader after voters in Scotland rejected independence in an historic referendum.
Deputy First Minister Nicola Sturgeon has paid tribute to Alex Salmond, after he announced he would be leaving his post in the wake of the independence referendum rejection.
In a full statement on her website, she praised Salmond's achievements whilst in office as "second to none."
Nicola Sturgeon also said that the personal debt she owed him was "immeasurable."
"Alex Salmond's achievements as SNP leader and Scotland's First Minister are second to none.
"He led the SNP into government and has given our country a renewed self confidence.
"Through policies such as the council tax freeze, free prescriptions and the scrapping of tuition fees, he has made a real difference for hundreds of thousands of Scots.
"And yesterday he inspired 1.6 million of our fellow citizens to vote Yes to independence.
"The personal debt of gratitude I owe Alex is immeasurable. He has been my friend, mentor and colleague for more than 20 years. Quite simply, I would not have been able to do what I have in politics without his constant advice, guidance and support through all these years."
North East leaders have welcomed Scotland’s decision to stay as part of the United Kingdom, but say now is the time to focus on devolving more powers to the North East of the country.
Councillor Nick Forbes, leader of Newcastle City Council, has raised his concerns that the regional cities will be "overlooked in the rush to settle with Scotland".
Speaking to Good Morning Britain, he also says it is "absolutely essential" that we get a new devolved approach to regions because without that change in power, "there will be increased resentment across England".
The leader of Newcastle City Council also says he thinks increased resentment could see the North East played into "dangerous politicians' hands".
Never mind Scotland, what about England? - Paul Brand, ITV Political Correspondent
With the Scottish question settled, minds are now turning to the English one. With promises of greater powers for the Scottish people now that they're staying, just what do you offer the English?
Many backbench MPs have been asking that for days, but have been keeping it quiet until the referendum was over. They're livid that the party leaders promised so much devolution to Scotland when the polls were looking tight, before discussing it with parliament. This morning the Prime Minister admitted that in considering more power for Scotland, there has to be consideration of England too.
Some of the main sticking points that will be examined in the coming days are whether Scottish MPs should be allowed to vote on English-only matters, and whether England should get its own parliament.
More than that, there is the incredibly complex and contentious issue of devolution for England's regions. A poll commissioned by ITV before the referendum shows 55% of people in the North East want an increase in powers for the region. But what should that look like?
The difficulty is that regional assemblies were rejected in 2004, and resoundingly. Equally, elected mayors have been a little hit and miss. What other models do you consider?
The parties speak about various options, including devolving powers to cities or Local Enterprise Partnerships. But that's a far more localised model of power than in Scotland, Wales and Northern Ireland. Can a city like Newcastle really hope to compete with a whole nation like Scotland?
There are no easy answers, and right now MPs are only just beginning to contemplate the question. After all, it is one that has never been asked quite like this before.
Politicians have all taken to twitter, using social media to voice their opinions following Scotland's 'No' vote to independence.Read the full story ›