Part of the A66 trans-pennine road between the North East and Cumbria had been closed overnight due to poor weather conditions.
It was shut between Brough and Bowes until around 1130 this morning as gritting teams worked to clear away snow and ice.
A stretch from Scotch Corner in North Yorkshire heading westbound was also closed for a time.
The A68 Eastbound is closed because of snow and two vehicle accident between B6278 and Pemberton Road.
Six other vehicles are stuck on the road due to the snow.
One lane is blocked and there is slow traffic because of an accident between a car and a lorry on the A1 Southbound between Boroughbridge(J48 A168 / A6055) and Allerton Park (J47 A168 / A59).
The onslip from New Bridge Street to the Central Motorway East, which was closed along with one lane of the CME while emergency services dealt with a collision, has now opened.
The two vehicles involved in the accident are awaiting recovery and there is still congestion in the area while the incident is cleared.
Northumbria Police believe nobody was seriously injured in the collision.
A two vehicle accident on the A167 Northbound between New Bridge Street/Durant Road (A193/B1309) and Sandyford Road (B1307) has caused blockages on two lanes on the motorway, according to police.
Both lanes on the A1 southbound are now following broken down vehicle near Dunston Road.
One lane remains closed northbound, so motorists are advised to use an alternative route if possible.
There is currently heavy traffic on the A1 in Gateshead and Newcastle, police say.
A broken down vehicle is currently blocking one lane southbound, just before Dunston Road.
One lane remains closed northbound at Blaydon Bridge due to damage caused to the barrier in a collision this morning.
Officers are in the area to help keep traffic disruption to a minimum.
Commuters on Tyneside are facing rush-hour chaos because of work to clean water pipes in Newcastle. Find out which routes will be effected:Read the full story ›
Drivers who have a daily thirty minute commute in the Newcastle Sunderland area spend nearly 70 hours a year in delays.
Data from the sat nav maker Tom Tom also shows congestion on secondary roads is worse than on main roads.
Passengers on the Tyne and Wear Metro are facing severe delays due to a technical problem.
The routes affected are between Haymarket and South Shields and between Haymarket and South Hylton.