The RMT Union has confirmed that cleaners on the East Coast Mainline and the Tyne & Wear Metro are striking for 48 hours.
The cleaners are in dispute with their contractors over their pay and conditions.
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His Royal Highness rounded off his visit to the region by giving a speech at Virgin Money headquarters in Newcastle.
Sunshine and showers tomorrow - but it is the calm before the storm.
Prince Harry joined Steve Cram and Jonathan Edwards in training those taking part in the London Marathon for charity Heads Together.