The Bubble Unit at Newcastle's Royal Victoria Infirmary will receive an award today.
The Jeff Modell Award is only given to one hospital in the world each year.
The Bubble Unit helps to treat children from the across the region, who have chronic conditions that affect their immune systems.
More top news
As October starts are we seeing more autumnal weather?
Sunderland boss David Moyes says agent's fees should be made public to keep football transparent after a week of allegations
The former X Factor winner, 28, has reached number one in the Official Singles Chart with Say You Won't Let Go.