The Bubble Unit at Newcastle's Royal Victoria Infirmary will receive an award today.
The Jeff Modell Award is only given to one hospital in the world each year.
The Bubble Unit helps to treat children from the across the region, who have chronic conditions that affect their immune systems.
More top news
BT has announced plans to recruit a further 90 staff in Newcastle as part of a UK-wide recruitment drive to transform customer service.
Police have criticised plans for 3,000 people to float on inflatables down the River Tyne while drinking beer.
The festival, organised by Durham County Council showcases a broad range of brass music, from Broadway to 17th Century Venice