Celebrities including Britain's Got Talent winner Jai McDowall and actor Tim Healy are taking part in a charity concert at St Nicholas Cathedral in Newcastle.
The event will raise money for Teenager Cancer Trust, and will go towards The Great North Children's Hospital and the Freeman Hospital, which provide specialist care for teenage cancer patients.
Emmerdale's Charlie Hardwick and Lindisfarne's Billy Mitchell will be giving readings at the event.
More top news
A look ahead at the forecast for the Tyne Tees region
A look ahead at the last weekend of the meteorological Summer.
William Hague, Sir Alan Beith and Anne McIntosh all appear in the Dissolution Honours list for 2015.