Sheila Nicholson is retiring at the age of 71, having started work at The Red Lion pub in Chester-le-Street since 1972 - when she took over from her mother.
There will be a celebration party at the pub for Mrs Nicholson and some of the regulars.
"Shelia is one of the best people I know.
She's such a lovely person and the team and I will be so sad to see her go. It's always a pleasure to come down in the morning and see Shelia.
She's an important part of the success of the pub and with her passion to making sure the pub is spotless; she leaves some very big shoes to fill.
There's no smudge, smear or dust that she can't spot."
More top news
A man was cut with a knife close to a primary school in York after he refused to hand over his mobile phone.
Chris Rea has cancelled a further concert following his collapse during a show on Saturday.
A man has been sentenced after he sexually assaulted a young woman on a cycle path.