Sheila Nicholson is retiring at the age of 71, having started work at The Red Lion pub in Chester-le-Street since 1972 - when she took over from her mother.
There will be a celebration party at the pub for Mrs Nicholson and some of the regulars.
"Shelia is one of the best people I know.
She's such a lovely person and the team and I will be so sad to see her go. It's always a pleasure to come down in the morning and see Shelia.
She's an important part of the success of the pub and with her passion to making sure the pub is spotless; she leaves some very big shoes to fill.
There's no smudge, smear or dust that she can't spot."
More top news
Stewart Anderson, 54, died in hospital following an incident outside the Loveshack nightclub in Durham in July.
Richmondshire residents are being asked if play areas should be designated ‘smoke free’ zones.
A romantic hopeful proposed to his girlfriend by flying her over a field where a farmer had mowed the words "will you marry me".