The cold snap is expected to "go out with a bang" on Friday, with the Met Office issuing amber warnings for the north of England.
The Highlands of Scotland will see the heaviest snowfall, while up to six inches could fall in northern England, four inches in the Midlands and two inches in the South.
The Met Office said it has amber warnings in place for much of Scotland, the north of England, east of England and East and West Midlands.
It warned that strong winds will also lead to drifting and blizzard-like conditions, particularly over higher level roads in the north.
– Sean Penston, forecaster at MeteoGroup
"By Saturday the sleet and snow will be lingering in eastern parts and Scotland and the North.
It is going to turn windy and there will be widespread rain across much of the country.
It seems like the worst of the cold weather is over, and there is no more snow forecast for the foreseeable future."