Northumbria University has offered 700 members of its staff the chance to apply for voluntary redundancy in an effort to make itself "more efficient and effective" in the future.
A spokesperson told ITV News that it was not expecting all 700 to take redundancy, but is offering the option to many people whose job has changed.
Academic support, communication, admin and IT staff are all part of the consultation.
More top news
Remain or Leave? The impact on business in the North East.
A dad from Sunderland who's won £1million on a scratchcard says he was concerned about how he was going to pay the bills
Another red kite has been found shot in North Yorkshire. Police are asking for help in the fight against persecution of the rare birds