The administrators for HMV have confirmed that the famous name will disappear from at least four of the region's high streets.
The branches in South Shields, Durham, Stockton and the Teesside Shopping Park will close, with the loss of thirty nine jobs.
Our Business Correspondent Ben Chapman visited the South Shields branch, where the shop has played its own part in recent pop music history.
His report, which you can watch in full below, contains some flash photography.
More top news
Kerrie Gosney brings you Sunday night's forecast for the Tyne Tees region
The remains of Hurricane Gonzalo will reach the UK on Monday night, bringing a period of strong winds and heavy rain to the UK.
An unsettled week with showers or rain and some very strong winds. There's a Met Office warning for gales as we head into Tuesday