The administrators for HMV have confirmed that the famous name will disappear from at least four of the region's high streets.
The branches in South Shields, Durham, Stockton and the Teesside Shopping Park will close, with the loss of thirty nine jobs.
Our Business Correspondent Ben Chapman visited the South Shields branch, where the shop has played its own part in recent pop music history.
His report, which you can watch in full below, contains some flash photography.
More top news
Why we should look out for UVA protection ratings - even in Spring
The current UK manufacturer has said it is disappointing this "icon of British identity" is set to be awarded to a Franco-Dutch firm.
The road was closed in both directions after the crash, which involved an HGV and transit van.