As part of ITV's From the Heart campaign, ITV Tyne Tees is looking at the issue of organ donation - and how to increase the number of donors.
NHS research conducted in Newcastle shows families asked whether they will donate a relative's organs shortly after their death say no 40% of the time. Even among those who have signed the organ donor register, expressing a wish to donate, one in ten families says no.
Every year 355 people get a transplant. But every day in the UK, 3 people die waiting for one.
Patients at Dumfries and Galloway Royal Infirmary put up with gruelling dialysis, waiting for a transplant that could change their lives.