A1 southbound closed due to fuel spillage and accident, two lorries involved from Stannington Station Road (Stannington Station / Services Turn Off) to Main Street (Stannington North / Netherton Park Turn Off).
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Chancellor George Osborne will seek to reassure financial markets on Monday morning following Britain's decision to leave the EU.
Eight crew members had to be rescued from a fishing boat after it started sinking a mile off the coast of Sunderland.
Drivers travelling north or southbound on the A1 near Newcastle and Gateshead are advised to expect delays until Wednesday morning.