Jobs in Darlington will be supported by a new multibillion-pound Crossrail project on the Maidenhead to east London route.
Crossrail will support around 55,000 full-time jobs in total - including those in Darlington.
– Andrew Wolstenholme, Crossrail chief executive
"Crossrail will not just benefit London and the South East - the project's economic benefits are being felt well beyond the confines of the M25.
"Firms right across the UK are winning business on the back of Europe's largest construction project. Work is set to peak over the next two years, so it's vital that businesses continue to seize the opportunities that Crossrail has to offer."
Contracts worth 5.5 billion pounds have already been awarded, with 43% given to businesses outside London and the South East.
Firms in Darlington in County Durham are among those awarded contracts, said Crossrail.
Three out of five firms in the supply chain are small to medium sized enterprises.
Total funding for the 73-mile rail route from Maidenhead to east London, due to open in 2018, is 14.8 billion pounds, with most contracts in the supply chain yet to be awarded.
Over 1,700 businesses have secured work connected to the project so far.
– Vince Cable, Business Secretary
"Crossrail is the type of project that will help the UK build a stronger economy by improving our infrastructure and creating jobs across the country.
"With over £5.5 billion of contracts awarded and 75,000 business opportunities throughout the supply chain, this is now the time for the UK's small and medium companies to capitalise."