The A1 is closed in both directions at Alnwick with queuing traffic due to accident between B1340 (Alnwick) and B6341 (South Charlton).
Police are on the scene.
The accident happened on the Northbound side at around 5.40pm.
Diversions are in place - for Northbound traffic travel via Denwick, and for Southbound traffic via South Charlton.
More top news
A look ahead at the Bank Holiday forecast for the Tyne Tees region.
Do you want to Leave or Remain in the European Union? That's the question facing everyone in the country. But what do young people think?
Remain or Leave? The impact on agriculture in the North East