The A174 Parkway eastbound is closed - queueing traffic due to an accident involving a bus, a lorry, a van and three cars between the A19 roundabout and the A1044 Low Lane.
It is causing congestion on the A19 northbound to the A67 (Crathorne).
The road is closed towards Lazenby and is likely to remain closed into this afternoon.
There are also long delays on the Parkway westbound.
More top news
Northumbria Police is launching its biggest recruitment campaign in nearly a decade as they look to take on hundreds of recruits.
A drunk man swimming in the Tyne harbour sparked the launch of Tynemouth RNLI lifeboat and other emergency services early this morning.
Average earnings rise in the region according to new prosperity map - but North East still lags behind