Helen Ford has been finding out how the People's Millions grants have helped improve lives.
She revisited Lynn McManus - a winner from last year - to find out about her story.
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Pam Royle has been along to surprise this year's ITV Tyne Tees Fundraiser of the Year.
The breakthrough by Newcastle scientists could save the sight of thousands worldwide.
The touring stage show is on at the Empire and ITV Tyne Tees couldn't resist the opportunity to check out the fun and flares back stage.