Police and Fire officers are currently at the scene of a large blaze at Godwins Furniture Store on Norton Road in Stockton.
The fire is causing a great deal of smoke in the local area and officers are asking people in living nearby to keep their windows closed.
Those living in the surrounding houses have been asked by police to stay indoors.
Drivers are being asked to avoid the area if possible.
It is not thought that anyone is inside the building.