The A66 in Middlesborough will be closed for four hours after two 40ft long steel pipes came off the back of an HGV.
It's thought a second HGV then crashed into the pipes. No one was hurt.
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Macmillan Cancer Support’s mobile service will be visiting the region, with cancer information specialists on hand to answer questions.
Enquiries are ongoing and police are appealing for information after the incident.
South Tyneside Council say despite its financial pressures, it is committed to regeneration, economic growth and job creation in the borough