Nine men and one woman were arrested in early morning raids across Newcastle.
The co-ordinated strikes at 15 addresses were part of Operation Magnet, a long-running investigation into drug dealing by an organised crime group in the city.
The men, aged between 22 and 46, were all arrested on suspicion of conspiracy to supply controlled drugs.
A 46-year-old woman was arrested on suspicion of attempting to conceal criminal property.
More top news
Ant McPartlin declared it was "good to be back" as he returned to television screens for the first time since his stint in rehab.
The UK's largest light festival has drawn to a close in Durham with those behind it saying this year's event has exceeded all expectations.
The former lead singer of AC/DC has paid a loving tribute to the band's co-founder, who 'has left a legacy few can match'.