A coach heading for Newcastle has collided with a lorry on the A1.
Thirteen people, two drivers and eleven passengers, have been taken to hospital.
Two are seriously ill.
The crash happened at 5.30am in Cambridgeshire.
It involved a chartered coach and a Tesco lorry.
More top news
Middlesbrough have failed to win any of their last five matches, and find themselves in the bottom half of the table
Ministers are ready to reduce the waiting time for Universal Credit payments following an outcry from Tory MPs, it has been suggested.
Three campaigners are occupying a work-over rig at Kirby Misperton in North Yorkshire to protest over plans to frack at the site.