James Ramsbotham, Chief Executive of the North East Chamber of Commerce, says companies like Nissan need to know whether the UK will remain in the EU.
The head of the Japanese car company, Carlos Ghosn, has claimed they would "reconsider" their position if the UK left the EU.
This would threaten jobs at Nissan's plant in Sunderland, which employs 6,500 people.
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A look ahead at the weekend weather for the Tyne Tees region.
Exmoor ponies have proved to be such a success for the habitat at a South Tyneside nature reserve that they've been brought back.
A replacement bridge on one of Stockton Borough's busiest roads has opened well ahead of schedule.