- Tyne Tees
James Ramsbotham, Chief Executive of the North East Chamber of Commerce, says companies like Nissan need to know whether the UK will remain in the EU.
The head of the Japanese car company, Carlos Ghosn, has claimed they would "reconsider" their position if the UK left the EU.
This would threaten jobs at Nissan's plant in Sunderland, which employs 6,500 people.
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Councils flew Saltires while people in South Shields signed a petition calling for our neighbours to stay in the union.
In an exclusive poll, ITV News Tyne Tees and ComRes found 65% of Tyne Tees residents do not want Scotland to become an independent country.
Children born in parts of the North East could be expected to live 15 fewer years in good health when compared with parts of the south.