Neil Foster, Northern TUC, has said that the region's economy would be left shaken if Nissan left the UK. It comes after the chief executive of Nissan said he would reconsider the car maker's future in the UK if it left the European Union.
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He was told he was being let go by the Magpies in May.
A joint bid could see Hartlepool, Middlesbrough, Stockton, Redcar and Cleveland, Darlington the region become a cultural capital.
Witnesses say they were told to stay in their homes after the incident last night.