Kadcyla, a drug that can offer some women with advanced breast cancer nearly six months of extra life, which was trialled here in the North East, has for now been rejected for use in the NHS, because of its high cost.
A Newcastle doctor whose patients have been involved in the clinical trials is disappointed by the decision.
Dr Mark Verrill, from the Freeman Hospital, say the drug is revolutionary.
More top news
A look ahead at the forecast for the Tyne Tees region.
A report from the Royal Society for Public Health ranks Middlesbrough 2nd in its list of the towns with the least healthy high streets.
The Rugby World Cup Trophy, the Webb Ellis Cup will be in the North East from July 29 - August 8th during a tour of the UK and Ireland.