Superintendent Alan Veitch, from Northumbria Police, says he's very worried about missing woman Lynda Foulkes.
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It's been confirmed that the Marks and Spencer stores in both Stockton and Darlington will close in August.
It's part of the investigation into the disappearance of Donna Keogh from Middlesbrough in 1998 when she was just 17 years old.
The move is likely to lead to the loss of more than 1,500 jobs.