Middlesbrough are to face Everton at home in December.
The championship promotion-chasers triumphed on penalties following a goalless draw at Old Trafford .
Grant Leadbitter, Stewart Downing and Ben Gibson all managed to get the better of United goalkeeper Sergio Romero.
Boro goalkeeper Tomas Mejias saved from Rooney and Young as Boro advanced to the quarter-finals.
More top news
A head teacher has apologised for a “failure” which saw a child left behind on a school trip to London.
A look ahead at the forecast for the Tyne Tees region.
The Cullercoats Lifeboat crew were alerted just before 5pm to a man in difficulty in the sea.