Opposition sources say the car bomb in Aleppo hit an area close to a local security office. The Syrian Observatory for Human Rights said the explosion had killed and injured people in the area but gave no estimate on the number of casualties.
More top news
Julian Cadman, who is thought to have dual British-Australian nationality, became separated from his mother who was injured in the attack.
Wayne Rooney and his wife Coleen are expecting their fourth child, the couple have announced.
As the silence came to an end the crowd began to applaud and people shouted "I am not afraid!" in defiance of the attacks.