Before landing, the aircraft will do a flyover of Washington DC at approximately 1,500 feet near a variety of landmarks, including the National Mall, Reagan National Airport and the National Harbor.
Discovery retired in March after completing its 39th mission. It spent a total of 365 days in space, orbited the Earth 5,830 times, and travelled 148,221,675 miles.
More top news
Former ITN newscaster Gordon Honeycombe has died aged 79 in Australia, his family has said.
Because shooting is permitted all year round dependent pups are left to starve if their mothers are shot, says charity.
Businessman Shrien Dewani has accused authorities of a "witch hunt" against him, in his first public statement in years.