Before landing, the aircraft will do a flyover of Washington DC at approximately 1,500 feet near a variety of landmarks, including the National Mall, Reagan National Airport and the National Harbor.
Discovery retired in March after completing its 39th mission. It spent a total of 365 days in space, orbited the Earth 5,830 times, and travelled 148,221,675 miles.
More top news
An air steward notoriously blamed for starting the Aids epidemic in the US has been posthumously cleared of spreading the virus.
The Gangsta's Paradise singer was told if he is found with a single bullet on him in the next three years he could face jail.
Workers are also taking out payday loans and pawning their belongings just to get by, according to a survey by Unison.