Bob Bell, chief executive of the Royal Brompton & Harefield NHS Foundation Trust, said:
"It is very difficult to know what to say at times like these.
"But it is even more difficult to try and understand how this committee could have come to such a decision.
"I will now discuss this decision with the Trust's Board and Governors' Council to determine our next steps. One thing is certain - I will not be asking them for the mandate to manage the destruction of a highly valued and respected children's unit."
Hospitals in Leicester, Leeds and the Royal Brompton in London are to stop performing heart surgery on children, it has been announced.
The controversial review into the future of children's heart surgery could lead to the closure of heart centres in the UK.