Mountain Rescue England and Wales, who have contributed 9,250 man-hours to the search for April, are to step down their search this evening.
Simon Woodhead, from Mountain Rescue England and Wales, said:
We've now reached a point where we've exhausted the search of areas best suited to our skills given what we currently know.
"The tasks now being generated are suited more to specially trained police teams.
"As such Mountain Rescue operations will be suspended this evening."
He said Mountain Rescue workers, made up of teams that are funded by donations, would remain on hand and assist police if they need them.
The Machynlleth community came together in prayer in an emotionally charged service in honour of missing April Jones.
Mark Bridger has been charged with the abduction and murder of missing 5-year-old April Jones.