The UKDPC called for Parliament "to revisit the level of penalties applied to all drug offences and particularly those concerned with production and supply", but stopped short of calling for the decriminalisation or legalisation of most drugs.
The report, titled A Fresh Approach to Drugs, said:
We do not believe that there is sufficient evidence at the moment to support the case for removing criminal penalties for the major production or supply offences of most drugs.
But the commission said policy makers were failing to deal effectively with drugs - amid the rapid creation of new substances. The report added:
Seeing all drug use as invariably problematic can reduce the cost-effectiveness of policy. Just like with gambling or eating junk food, there are some moderately selfish or risky behaviours that free societies accept will occur and seek to limit to the least damaging manifestations, rather than to prevent entirely. Taking drugs does not always cause problems, but this is rarely acknowledged by policy makers.
More top news
The party's deputy-leader is the sole candidate in the race to succeed Gerry Adams.
A Met Office yellow "be aware" warning for ice is in place across much of Scotland, Northern Ireland and northern England.
Nick Boles warned the PM it was "time to raise your game" and claimed her government "constantly disappoints" in a tweet.