At least 10 people have been killed and many others wounded in the car bombing near a police station in Bab Touma in old Damascus, ITV News understands.
Syrian official sources confirmed the latest death toll. They said the bomb was placed under the vehicle and caused huge damage to the neighbourhood, which is mostly inhabited by minority Christians.
More top news
Net migration to Britain was down 49,000 in the year to September 2016, the lowest level in more than two years.
Special forces say they have attacked a sprawling site adjacent to the city's airport in a bid to liberate the area from IS.
Flights and trains were cancelled or delayed and drivers were warned to steer clear of some main roads as winds of nearly 90mph hit.