Rockets bombarded southern Israel in retaliation for Israeli aircraft, tanks and naval gunboats pounding the Hamas-ruled Gaza Strip.
Ten Palestinians were killed yesterday on the operation's first day and more than 93 were wounded, while Israeli television reported that three people had been killed from a rocket strike from Gaza.
The operation started after the assassination of Hamas' top military commander, Ahmed Jabari, in response to days of rocket fire from the Palestinian territory.
Jabari's death was followed by a wave of Israeli airstrikes on more than 100 militant targets.
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Today's bombing in Tel Aviv is reminiscent of six years ago and could mark a serious escalation in the conflict.
A truce in Gaza suits all sides but none of the groups seem interested in a long-lasting solution.
A complex system of air defences has been instrumental in protecting Israel's population from incoming rockets.