Over the past few years, Patrick, an inspiration to generations of astronomers, fought his way back from many serious spells of illness and continued to work and write at a great rate, but this time his body was too weak to overcome the infection which set in, a few weeks ago.
He was able to perform on his world record-holding TV Programme The Sky at Night right up until the most recent episode.
His executors and close friends plan to fulfil his wishes for a quiet ceremony of interment, but a farewell event is planned for what would have been Patrick's 90th birthday in March 2013.
More top news
Scientists concluded 12.5% of cardiovascular deaths could be avoided if more Britons changed their diets.
Chelsea Clinton has brushed off Donald Trump's threat to bring up her father's infidelities in a recent interview.
Sir Tom will be joined on the panel by Oscar-winning actress and singer Jennifer Hudson and rock star Gavin Rossdale.