Home Office Minister Jeremy Browne said the Government was "open to new ways of thinking" about the drugs debate.
"We are open-minded, we think it's a decent, thoughtful, balanced report. We will consider it carefully," he said to the BBC Radio 4 Today programme.
The Home Secretary has said she doesn't think the Royal Commission is the answer at this time, but we are open to new ideas and evidence-based research to carry on reducing the harm caused by drugs in this country.
Pressed on whether the Government would hold a Royal Commission as suggested, Mr Browne said the Home Secretary did not think that was the right approach.
More top news
Police have arrested three teenagers and a man following the shooting of a three-year-old girl with an air gun.
Police have released new images of the site of the fatal crash near Shoreham Airshow in which at least 11 people died.
Ministers have deployed a new weapon to combat Islamic State - a dedicated Twitter feed.