Air Bagan said the plane, which was carrying 63 passengers and six crew members, was forced to make an "emergency landing".
Witnesses said smoke filled the plane when it hit the ground and was still rising from the plane's badly charred wreckage hours later.
Airport officials in Heho said that injured passengers were taken to a hospital in the nearby city of Taunggyi for treatment.
More top news
Zayn Malik has spoken for the first time since quitting 1D saying he was upset to let fans down but that it wasn't "real" to him anymore
Coronation Street actress Samia Ghadie has announced she is expecting her first child with ice dancer Sylvain Longchambon.
Patrick Berger has moved quickly to deny reports he was supposed to be on the tragic Germanwings flight from Barcelona to Dusseldorf.