A police department spokesperson said one of the 57 people injured appeared to be in critical condition.
"People were thrown into the air and onto the ground," passenger Elizabeth Banta told CNN. "There were definitely many people on the ground who were not moving."
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Temperatures will feel a little milder compared to of late with highs reaching 14C (57F).
Dozens of common treatments to help with a range of ailments are apparently of little or no use.
The prime minister has offered Scotland, Wales and Northern Ireland a "direct line" to Brexit Secretary David Davis.