David Cameron will call for greater international cooperation on tax evasion in a speech to the World Economic Forum at Davos.
The Prime Minister will urge leaders to work together and tackle tax evasion by multi-national companies and the super-rich.
Mr Cameron will make the issue a key focus during Britain's presidency of the G8 leading economic powers.
A Downing Street spokesman said he would not be talking about Europe in the wake of his landmark promise of a referendum.
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The prime minister has offered Scotland, Wales and Northern Ireland a "direct line" to Brexit Secretary David Davis.