A spokesman for Ladbrokes has said the firm is "not prepared to offer long odds" on the HS2 line being subject to delays, alterations and cancellations.
The bookmaker is currently offering 4/5 that there will be delays when it comes to the opening of the service.
The government expects to complete the first phase of the high speed route from London to Birmingham by 2026, with the Manchester and Leeds extension being finished by 2033.
More top news
A man became so frustrated with noise from a nearby building site that he shot a builder with an air rifle, according to police.
A backbench revolt over proposals to ease purdah restrictions on the EU referendum has led to a government climb down.
It's been a colder start to the day, especially in rural areas of Britain.