President Barack Obama has said John Kerry will make an "extraordinary Secretary of State," following his confirmation by the Senate.
President Obama said: "I am pleased that the Senate has confirmed John Kerry as our next Secretary of State with overwhelming bipartisan support.
"From his decorated service in Vietnam to his decades in the Senate as a champion of American global leadership, John’s distinguished career has prepared him to guide American diplomacy in the years ahead.
"John has earned the respect of leaders around the world and the confidence of Democrats and Republicans in the Senate, and I am confident he will make an extraordinary Secretary of State.
"I look forward to his counsel and partnership in the years ahead as we ensure American leadership in the world and advance the interests and values that keep our nation strong."