John Kerry hailed the contribution of outgoing Secretary of State Hillary Clinton at his official swearing in ceremony in Washington.
"I want to thank Secretary Clinton for the unbelievably high standard of energy, commitment and vision that she set in her superb stewardship of the US State Department," said Kerry.
The new Secretary of State also paid tribute to Barack Obama, saying: "The President has restored American's place and our reputation in the world."
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ITV Border Political Editor Peter MacMahon says it's far too early to call this referendum.
A World War Two veteran has told ITV News he has fulfilled a boyhood dream by voting for an independent Scotland.
Speaking as a Scot - not the ITV News Scotland Correspondent - I am feeling a great anxiety about what lies ahead.