The Metropolitan Police confirmed the two men arrested as part of Operation Fernbridge on suspicion of sexual offences are currently in police custody.
The men are (a) aged 66 from Norfolk, and (b) aged 70 from East Sussex.
Both are in police custody at this time.
Commander Peter Spindler, head of the MPS Specialist Crime Investigations, said:
This is a complex multi-agency investigation supported by the NSPCC, CEOP and Richmond Social Services involving non recent allegations of sexual assault against children.
It is vital that anyone who has been affected by or has information about activity in the early 1980s at the Elm Guest House, or the Grafton Close care home, in Barnes speaks to the NSPCC on their Helpline on 0808 800 5000, or their local police.
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